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Arboviral Threats Ahead: Addressing the Global Rise of Chikungunya and Japanese Encephalitis in the Age of Travel and Climate Change On-Demand

Introduction

Arboviruses (arthropod-borne-virus) are transmitted by arthropods such as blood-sucking insects like mosquitoes, and multiply in vertebrates. Aedes spp. mosquitos are one of the vectors for arboviruses like chikungunya virus (CHIKV) and dengue virus, both commonly transmitted by Aedes albopictus. The Japanese encephalitis virus (JEV) is primarily spread by Culex mosquitoes.1,2 

Over the past century, Aedes albopictus mosquitoes have spread from their natural habitat in Africa to other continents, mostly triggered by increased trade, travel habits, urbanization, and climate change, posing a major global public health threat.1,2

It is important to note that autochthonous cases of JE have not yet been reported in Europe or the USA. However, the history of chikungunya and other widespread arboviruses highlights the need for preparedness measures in these regions.2,3  Of note, JE is widespread in Asian-Pacific countries but there have been reports of finding JE RNA in birds as well as a pool of Culex pipiens mosquitoes sampled in Italy.2

In conclusion, urgent educational initiatives are needed to strengthen preparedness for the potential emergence of arbovirus cases in the USA and Europe.

Arboviral Threats Ahead: Addressing the Global Rise of Chikungunya and Japanese Encephalitis in the Age of Travel and Climate Change

Faculty

David H. Hamer, Prof. MD, FACP, FIDSA, FASTMH, FISTM, Department of Global Health and Medicine, Boston University School of Public Health, Boston, MA, USA

Tom Solomon, Prof. CBE, FRCP, FMedSci, Chair of Neurological Science, University of Liverpool and Director of The Pandemic Institute

Aileen Maria Marty, Distinguished U Prof. MD, FACP, Translational Medicine,Division of Internal Medicine, FIU Herbert Wertheim College of Medicine, Miami, FL, USA

Sarah McGuinness, MBBS, FRACP, MPH&TM, PhD, Department of Infectious Diseases, Alfred Health and School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

Learning Goals/Purposes

The goal of this project is to provide education for HCPs involved in the care of individuals with  disease across a variety of clinical settings, specifically focusing on:

  • Provide an overview of arboviral diseases, focusing on CHIKV and JEV. Discuss the rising global threat posed by these diseases, with emphasis on epidemiology and the spread over the last decades.

  • Explore how climate change, travel patterns, urbanization, and other factors contribute to the increased incidence of arboviral diseases like CHIKV and JEV.

  • Discuss real-world patient cases simulations  to review risk factors, diagnosis, and prevention strategies for both CHIKV and JEV vaccination, and vector control, while addressing limitations.

  • Summarize the most important topics HCPs should cover in pre-travel consultations to help travelers reduce the risk of CHIKV and JEV infections.

Learning objectives

After completing this educational activity, learners should be able to:

  • Identify the global epidemiology of CHIKV, JEV, and other arboviruses, their life cycles, and their potential spread to non-endemic areas
  • List and evaluate the effectiveness of various prevention and control measures for CHIK and JEV infections and other arboviruses, including personal and community protective measures to avoid mosquito bites and eliminate breeding places (i.e., insecticide use)
  • Recognize and identify the populations most at risk for CHIK, JE, or other arboviral infections, and offer pre-traveling counseling and vaccinations if indicated
  • Recognize the clinical presentations of CHIK, including both acute and chronic forms, JE symptomatology, and other arbovirus infections, and identify relevant diagnostic tools and investigations to facilitate prompt differential diagnosis
  • Outline therapeutic goals and list symptomatic treatments recommended in cases of infection, and apply best practices in managing different stages of disease, focusing on pain management and disability prevention
  • Apply effective patient education strategies to increase public awareness and reduce the likelihood of transmission in high-risk populations, enhancing patient–doctor pre-travel counselling and providing resources (e.g., WHO, US and European CDCs).
  • Describe the need for and foster collaborative initiatives aimed at ensuring equitable access to affordable vaccines, and establish preventive measures in vulnerable populations.
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Target Audience

This educational activity is intended for healthcare professionals involved in the care of individuals at risk for or affected by tropical diseases such as Chikungunya and Japanese Encephalitis.

The target audience includes infectious disease specialists, tropical medicine physicians, orthopedists, nurse practitioners, physician assistants, nurses, and pharmacists practicing in global settings.

Enduring Materials CE Activity

Release Date: July 8, 2025

Expiration Date: October 20, 2026

Continuing Education Information

This continuing education activity is provided by AffinityCE and  Skymedcare LLC. This activity provides continuing education credit for physicians, physician assistants, nurse practitioners, and nurses. A statement of participation is available for other attendees.

Disclosures

Faculty disclosures

Dr. David Hamer, has disclosed the following financial relationships:

  • Consultant for Bavarian Nordic, Takeda, Valneva; Speaker for Medscape, Bavarian Nordic; and receives research funding from Merck & Co and Takeda.

Dr. Tom Solomon,has disclosed the following financial relationships:

  • Grant support from MRC, NIHR, Wellcome; Research support from Innova, CSL Seqirus, AstraZeneca and Aviva.

Remaining Faculty members have no relevant financial relationships to disclose.

AffinityCE staff, Skymedcare staff, planners, and reviewers have no relevant financial relationships to disclose. All faculty disclosures are listed above, available on the program website, and will be stated prior to the start of each presentation.

Mitigation of Relevant Financial Relationships

AffinityCE adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant financial relationships reported have been mitigated prior to the commencement of the activity through peer review of content by non-conflicted reviewers.

Physicians

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and Skymedcare. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.

AffinityCE designates this enduring materials activity for a maximum of 2 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physician Assistants

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and SEI-Healthcare. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.

AffinityCE designates this enduring materials activity for a maximum of 2 AMA PRA Category 1 Credit™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioners

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and Skymedcare. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.

AffinityCE designates this enduring materials activity for a maximum of 2 AMA PRA Category 1 Credit™. Nurse Practitioners should claim only the credit commensurate with the extent of their participation in the activity.

Nurses

Continuing Nursing Education is provided for this activity through the joint providership of AffinityCE and Skymedcare. AffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation (ANCC). This activity provides 2.0 contact hour of continuing nursing education credit.

Pharmacists

AffinityCE is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education (CPE). This knowledge-based CPE activity will provide 2.0 contact hour for participants. There is no cost to participate. Participant CE records will be electronically communicated to CPE Monitor. UAN: 0829-999-25-088-H01-P

Other Professionals

All other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity.

Commercial Support

Educational Support for this activity was provided by an independent medical educational grant from Valneva Austria GmbH.

Participation Costs

There is no cost to participate in this CE activity.

CME Inquiries

For all CME policy-related inquiries, please contact us at info@my-ime.com

How to Earn CE Credit

Physicians, Physician Assistants, Nurse Practitioners, Nurses and other health professionals

1.Go to the following web site:https://my-ime.com/

2.Register or enter your profile ID.

3.Complete the activity. Your CE records will be made available via your Dashboard on My-Ime.com.

Accessing the Program

To join this accredited educational program, please complete your enrollment details.

This is the enduring, on-demand version of the in-person symposium and includes:

  • A brief pre-test and knowledge check. 
  • A full video recording of the symposium, available to view at your convenience. 
  • Two text-based patient vignettes that were discussed during the symposium, available for review within the platform.

CME Accreditation

To be eligible for your CME credits, you must:

  • Complete the full program. 
  • Successfully complete the post-test and submit the evaluation form within the platform.

Once enrolled, you can log in at any time using your registered email and password via the Login button at the top left-hand corner of the website.

References:

1.     Meyding-Lamadé U, Craemer E, Schnitzler P. Emerging and re-emerging viruses affecting the nervous system. Neurol Res Pract. 2019;1:20. doi: 10.1186/s42466-019-0020-6.

2.     Monath TP. Japanese encephalitis: risk of emergence in the United States and the resulting impact. Viruses. 2023;16(1):54. doi: 10.3390/v16010054.

3    Gossner CM, Dhollander S, Presser LD, Briet O, Bakonyi T, Schaffner F, Figuerola J. Potential for emergence of Japanese encephalitis in the European Union. Zoonoses

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Disclaimer

This independent medical education program has been supported by an independent medical educational grant from Valneva Austria GmbH. The educational program has been developed by SkymedCare in cooperation with AffinityCE, and it is intended for healthcare professionals practicing globally.

The information presented is not intended as medical advice. Responsibility for patient care resides with the healthcare professional on the basis of their professional license, experience, and knowledge of the individual patient. For full prescribing information for all products, including indications, contraindications, warnings, precautions, and adverse events, please refer to the approved product labeling. Please note that products may have different product labeling according to geographical location, within the United States, full prescribing information is available from the US Food and Drug Administration (fda.gov). For other regions, consult the relevant regulatory authorities, such as Health Canada (canada.ca/en/health-canada), the European Medicines Agency (ema.europa.eu), the UK Medicines and Healthcare products Regulatory Agency (gov.uk/mhra), Australia’s Therapeutic Goods Administration (tga.gov.au), Japan’s and Pharmaceuticals and Medical Devices (pmda.go.jp). For global guidance, refer to the World Health Organization (who.int).  

All characters and events depicted in this activity are entirely fictitious. Any similarity to actual events or persons, living or dead, is purely coincidental.

The information presented is not intended as medical advice. Responsibility for patient care resides with the healthcare professional on the basis of their professional license, experience, and knowledge of the individual patient.